Article
Long-term outcome of entecavir treatment of nucleos(t)ide analogue-naïve chronic hepatitis B patients in Japan.
Journal of gastroenterology - 1 Feb 2019
Suzuki Fumitaka, Hosaka Tetsuya, Suzuki Yoshiyuki, Sezaki Hitomi, Akuta Norio, Fujiyama Shunichiro, Kawamura Yusuke, Kobayashi Masahiro, Saitoh Satoshi, Arase Yasuji, Ikeda Kenji, Kobayashi Mariko, Mineta Rie, Suzuki Yukiko, Kumada Hiromitsu
Abstract excerpt
BACKGROUND: We determined the antiviral potency and viral breakthrough rate after 10 years of continuous entecavir treatment in patients with chronic hepatitis B (CHB) infection. METHODS: The cumulative rates of undetectable hepatitis B virus DNA (HBV-DNA, < 2.1 log copies/mL), alanine aminotransferase (ALT) normalization, hepatitis B e antigen (HBeAg) seroclearance, hepatitis B surface antigen (HBsAg)...
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