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Article

The CSC is required for complete radial spoke assembly and wild-type ciliary motility.

Molecular biology of the cell - 15 Jul 2011

Dymek Erin E, Heuser Thomas, Nicastro Daniela, Smith Elizabeth F

Abstract excerpt

The ubiquitous calcium binding protein, calmodulin (CaM), plays a major role in regulating the motility of all eukaryotic cilia and flagella. We previously identified a CaM and Spoke associated Complex (CSC) and provided evidence that this complex mediates regulatory signals between the radial spokes and dynein arms. We have now used an artificial microRNA (amiRNA) approach to reduce expression of two CSC...

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Identifiers

PMID: 21613541
DOI: 10.1091/mbc.E11-03-0271
PMCID: PMC3135477

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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