Article
Evaluation of serum lipid concentrations and genetic variants at high-density lipoprotein metabolism loci and TIMP3 in age-related macular degeneration.
Investigative ophthalmology & visual science - 25 Jul 2011
Fauser Sascha, Smailhodzic Dzenita, Caramoy Albert, van de Ven Johannes P H, Kirchhof Bernd, Hoyng Carel B, Klevering B Jeroen, Liakopoulos Sandra, den Hollander Anneke I
Abstract excerpt
PURPOSE: To analyze the association between polymorphisms in the TIMP3 gene and genes of the high-density lipoprotein (HDL) metabolism and age-related macular degeneration (AMD), and evaluate serum lipid and lipoprotein levels in AMD patients compared with control individuals. METHODS: Single nucleotide polymorphisms in or near the TIMP3, ABCA1, FADS1-3, CETP, LIPC, and LPL genes were genotyped. Serum levels of...
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