Article
Recognition of Pathogenic Microbes by the Drosophila Phagocytic Pattern Recognition Receptor Eater
26 May 2011
Abstract excerpt
Non-opsonic phagocytosis is a primordial form of pathogen recognition that is mediated by the direct interaction of phagocytic receptors with microbial surfaces. In the fruit fly Drosophila melanogaster, the EGF-like repeat containing scavenger receptor Eater is expressed by phagocytes and is required to survive infections with gram-positive and gram-negative bacteria. However, the mechanisms by which this...
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