Article
Translating pharmacogenetics into clinical practice: interleukin (IL)28B and inosine triphosphatase (ITPA) polymophisms in hepatitis C virus (HCV) infection.
Clinical chemistry and laboratory medicine - 1 Aug 2011
Cariani Elisabetta, Villa Erica, Rota Cristina, Critelli Rosina, Trenti Tommaso
Abstract excerpt
Hepatitis C virus (HCV) infection is frequently characterized by evolution to chronicity and by a variable clinical course of the disease. The clinical heterogeneities of HCV infection and the imperfect predictability of the response to interferon (IFN) have suggested the need to search for a genetic basis of clinical features. This led to the discovery of genetic polymorphisms playing a major role in the...
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