Article
Interleukin28B and inosine triphosphatase help to personalize hepatitis C treatment.
Digestion - 1 Jan 2011
Tanaka Yasuhito
Abstract excerpt
In the therapy using a combination of pegylated interferon-α and ribavirin (PEG-IFN/RBV) for chronic hepatitis C (CHC), approximately 50% of CHC patients infected with high viremia of HCV genotype 1 reached sustained viral response. The recent discovery revealed by a genome-wide association study technology provides the unexpected role of IL28B and inosine triphosphatase (ITPA) in HCV infection. The former single...
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