Article
Dual priming oligonucleotide-based multiplex PCR analysis for detection of BRAFV600E mutation in FNAB samples of thyroid nodules in BRAFV600E mutation-prevalent area.
Head & neck - 1 Apr 2010
Kwak Jin Young, Kim Eun-Kyung, Kim Jong-Kee, Han Jeong-Hyun, Hong Soon Won, Park Tae Sung, Choi Jong Rak
Abstract excerpt
BACKGROUND: To evaluate the diagnostic value of dual priming oligonucleotide (DPO)-based multiplex polymerase chain reaction (PCR) for the detection of BRAF(V600E) mutations in ultrasound-guided fine-needle aspiration biopsy (US-FNAB) of thyroid nodules. METHODS: Our institutional review board ap...
Topics
- Adult
- Aged
- Biopsy, Fine-Needle
- Carcinoma, Papillary
- DNA, Neoplasm
- Female
- Humans
- Immunohistochemistry
- Male
- Middle Aged
- Mutation
- Oligonucleotides
- Polymerase Chain Reaction
- Polymorphism, Restriction Fragment Length
- Proto-Oncogene Proteins B-raf