Article
Dual priming oligonucleotide-based multiplex PCR analysis for detection of BRAFV600E mutation in FNAB samples of thyroid nodules in BRAFV600E mutation-prevalent area.
Head & neck - 1 Apr 2010
Kwak Jin Young, Kim Eun-Kyung, Kim Jong-Kee, Han Jeong-Hyun, Hong Soon Won, Park Tae Sung, Choi Jong Rak
Abstract excerpt
BACKGROUND: To evaluate the diagnostic value of dual priming oligonucleotide (DPO)-based multiplex polymerase chain reaction (PCR) for the detection of BRAF(V600E) mutations in ultrasound-guided fine-needle aspiration biopsy (US-FNAB) of thyroid nodules. METHODS: Our institutional review board approved this retrospective study, and informed consent was not required from patients. The 130 patients underwent...
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