Transmembrane protein structure: spin labeling of bacteriorhodopsin mutants.

doi:10.1126/science.2160734

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Article

Transmembrane protein structure: spin labeling of bacteriorhodopsin mutants.

Science (New York, N.Y.) - 1 Jun 1990

Altenbach C, Marti T, Khorana H G, Hubbell W L

Abstract excerpt

Transmembrane proteins serve important biological functions, yet precise information on their secondary and tertiary structure is very limited. The boundaries and structures of membrane-embedded domains in integral membrane proteins can be determined by a method based on a combination of site-spe...

Topics

Amino Acid Sequence
Bacteriorhodopsins
Cysteine
Electron Spin Resonance Spectroscopy
Membrane Proteins
Molecular Sequence Data
Mutation
Oxalates
Oxalic Acid
Oxygen
Protein Conformation
Spin Labels

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