Article
Sizing and phenotyping of cellular vesicles using Nanoparticle Tracking Analysis.
Nanomedicine : nanotechnology, biology, and medicine - 1 Dec 2011
Dragovic Rebecca A, Gardiner Christopher, Brooks Alexandra S, Tannetta Dionne S, Ferguson David J P, Hole Patrick, Carr Bob, Redman Christopher W G, Harris Adrian L, Dobson Peter J, Harrison Paul, Sargent Ian L
Abstract excerpt
Cellular microvesicles and nanovesicles (exosomes) are involved in many disease processes and have major potential as biomarkers. However, developments in this area are constrained by limitations in the technology available for their measurement. Here we report on the use of fluorescence nanoparticle tracking analysis (NTA) to rapidly size and phenotype cellular vesicles. In this system vesicles are visualized by...
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