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Article

Activation of the receptor NKG2D leads to production of Th17 cytokines in CD4+ T cells of patients with Crohn's disease.

Gastroenterology - 1 Jul 2011

Pariente Benjamin, Mocan Iulia, Camus Matthieu, Dutertre Charles-Antoine, Ettersperger Julien, Cattan Pierre, Gornet Jean-Marc, Dulphy Nicolas, Charron Dominique, Lémann Marc, Toubert Antoine, Allez Matthieu

Abstract excerpt

BACKGROUND & AIMS: The natural killer group 2 member D (NKG2D) is a stimulatory receptor expressed on a subset of mucosal and peripheral CD4+ T cells in patients with Crohn's disease (CD) and other inflammatory diseases. Ligand activation of NKG2D in patients induces CD4+ T cells to release T-hel...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to NK Cell Lectin-Like Receptor Subfamily K

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Source

Identifiers

PMID: 21600899
DOI: 10.1053/j.gastro.2011.03.061

Genes

CCR6
RORC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-21600899-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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