Article
Risk of canine cranial cruciate ligament rupture is not associated with the major histocompatibility complex.
Veterinary and comparative orthopaedics and traumatology : V.C.O.T - 1 Jan 2011
Clements D N, Kennedy L J, Short A D, Barnes A, Ferguson J, Ollier W E R
Abstract excerpt
OBJECTIVES: To investigate the association of the major histocompatability (MHC) class II allele haplotype frequencies with the diagnosis of cranial cruciate ligament (CCL) rupture in two breeds of dog. METHODS: DNA samples from populations of Labrador Retrievers and Golden Retrievers with CCL rupture and general populations of the same breeds were characterised for three DLA class II loci (DRB1*, DQA1* and...
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