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Article

Effect of doxycycline on contralateral canine cranial cruciate ligament rupture. A prospective randomized clinical trial in 69 dogs.

Veterinary and comparative orthopaedics and traumatology : V.C.O.T - 1 Jan 2015

von Pfeil D J F, Sung J, Barry J, Hayashi K, Edwards M R

Abstract excerpt

OBJECTIVE: To evaluate whether doxycycline administered to dogs with unilateral cranial cruciate ligament rupture (Uni-CCLR) would decrease the risk of contralateral-CCLR (Co-CCLR). To evaluate predictors for Co-CCLR survival. To evaluate if a predisposition of Labrador Retrievers to Co-CCLR exists when compared to other breeds. METHODS: In this prospective randomized controlled clinical trial, 69 client-owned...

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PMID: 26423712
DOI: 10.3415/VCOT-15-02-0034

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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