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Article

Investigation of association between TLR9 gene polymorphisms and VKH in Japanese patients.

Ocular immunology and inflammation - 1 Jun 2011

Ito Ryuta, Ota Masao, Meguro Akira, Katsuyama Yoshihiko, Uemoto Riyo, Nomura Eiichi, Nishide Tadayuki, Kitaichi Nobuyoshi, Horie Yukihiro, Namba Kenichi, Ohno Shigeaki, Inoko Hidetoshi, Mizuki Nobuhisa

Abstract excerpt

PURPOSE: Vogt-Koyanagi-Harada (VKH) disease is an autoimmune disorder affecting melanocytes in the skin, eyes, inner ear, and meninges. The Epstein-Barr virus and cytomegalovirus (CMV) antigen have been hypothesized as possible triggering factors for the disease. Toll-like receptors (TLRs) play an important role in the induction of defense mechanisms of the innate and adaptive immune responses to microbial...

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Source

Identifiers

PMID: 21595536
DOI: 10.3109/09273948.2011.553981

Genes

TLR9

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