Article
KIR and HLA gene combinations in Vogt-Koyanagi-Harada disease.
Human immunology - 1 Jun 2008
Levinson Ralph D, Du Zeying, Luo Lihui, Holland Gary N, Rao Narsing A, Reed Elaine F, Rajalingam Raja
Abstract excerpt
Vogt-Koyanagi-Harada (VKH) disease is a putative autoimmune ocular inflammatory disease and is known to be associated with HLA-DR4 and -DR1 in Mestizos. We examined the genes encoding KIR receptors and human leukocyte antigen (HLA) class I ligands in patients with VKH disease and compared to published controls. We found trends toward more group B KIR haplogroups (p=0.059), with more activating KIR genes, in...
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