Article
The phenotype standardization project: improving pharmacogenetic studies of serious adverse drug reactions.
Clinical pharmacology and therapeutics - 1 Jun 2011
Pirmohamed M, Aithal G P, Behr E, Daly A, Roden D
Abstract excerpt
The ability to predict the risk for serious drug-induced adverse reactions first requires a large patient database for characterization and validation of genetic markers. The Phenotype Standardization Project (PSP) was initiated to standardize phenotypic definitions, thereby facilitating much-needed recruitment without sacrificing the reliability of patient classification. Three phenotypes have been considered in...
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