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Article

Using genome-wide association studies to identify genes important in serious adverse drug reactions.

Annual review of pharmacology and toxicology - 1 Jan 2012

Daly Ann K

Abstract excerpt

Genome-wide association (GWA) studies have detected novel associations for serious, idiosyncratic, adverse drug reactions including liver toxicity, hypersensitivity, skin rash, and myotoxicity. Human leukocyte antigen (HLA) genotype has been established as an important predictor of susceptibility to drug-induced liver injury, including injury with some drugs where immune-related toxicity was not suspected...

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Source

Identifiers

PMID: 21819236
DOI: 10.1146/annurev-pharmtox-010611-134743

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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