Article
Interstrain crosses enhance excision of Tc1 transposable elements in Caenorhabditis elegans.
Molecular & general genetics : MGG - 1 Jan 1990
Mori I, Moerman D G, Waterston R H
Abstract excerpt
We report here an unusual activation of the Tc1 transposable element system in Caenorhabditis elegans. Germline Tc1 activity, as measured by reversion of unc-22::Tc1 alleles, is elevated 50- to 100-fold by certain crosses. For example, unc-22::Tc1 reversion is 1 x 10(-3) in a mut-6 IV strain and less than 1 x 10(-6) in a non-mutator strain, but in the unc-22::Tc1 progeny of a cross between mut-6 hermaphrodites...
Topics
- Alleles
- Animals
- Caenorhabditis
- Crosses, Genetic
- DNA Transposable Elements
- Female
- Male
- Mutation
