Article
Tc1 transposition and mutator activity in a Bristol strain of Caenorhabditis elegans.
Molecular & general genetics : MGG - 1 Jun 1990
Babity J M, Starr T V, Rose A M
Abstract excerpt
In most strains of Caenorhabditis elegans with a low copy number of Tc1 transposable elements, germline transposition is rare or undetectable. We have observed low-level Tc1 transposition in the genome of the C. elegans var. Bristol strain KR579 (unc-13[e51]) resulting in an increase in Tc1 copy number and subsequent mutator activity. Examination of genomic blots from KR579 and KR579-derived strains revealed that...
Topics
- Animals
- Base Sequence
- Caenorhabditis
- DNA Transposable Elements
- Molecular Sequence Data
- Mutation
- Nucleic Acid Hybridization
- Polymorphism, Restriction Fragment Length