Article
Mitomycin C induces genomic rearrangements involving transposable elements in Drosophila melanogaster.
Molecular & general genetics : MGG - 1 Jan 1990
Georgiev P G, Korochkina S E, Georgieva S G, Gerasimova T I
Abstract excerpt
Mitomycin C was injected into the abdomen of male flies of the y2 sc1 waG strain of Drosophila melanogaster. They were mated with females bearing attached-X chromosomes, and the male offspring (F1) were analysed for the appearance of mutations in the X chromosome. We observed y+ and sc+ reversion...
Topics
- Animals
- Blotting, Southern
- DNA Transposable Elements
- Drosophila melanogaster
- Female
- Gene Rearrangement
- Male
- Mitomycin
- Mitomycins
- Mutation
- Recombination, Genetic
- Restriction Mapping
- X Chromosome
