Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Functional Characterization of Inflammatory Bowel Disease–Associated Gut Dysbiosis in Gnotobiotic Mice

3 Mar 2016

Abstract excerpt

BACKGROUND & AIMS: Gut dysbiosis is closely involved in the pathogenesis of inflammatory bowel disease (IBD). However, it remains unclear whether IBD-associated gut dysbiosis contributes to disease pathogenesis or is merely secondary to intestinal inflammation. We established a humanized gnotobiotic (hGB) mouse system to assess the functional role of gut dysbiosis associated with 2 types of IBD: Crohn's disease...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Clostridium difficile and Clostridium perfringens research
Share to Gut microbiota and health
Share to Inflammatory Bowel Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 27795980
DOI: 10.1016/j.jcmgh.2016.02.003

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Functional Characterization of Inflammatory Bowel Disease–Associated Gut Dysbiosis in Gnotobiotic MicePMID 27795980Read ↗

Functional Impacts of the Intestinal Microbiome in the Pathogenesis of Inflammatory Bowel DiseaseSemantic proximity Read ↗

Homeostasis and Dysbiosis of the Intestinal Microbiota: Comparing Hallmarks of a Healthy State with Changes in Inflammatory Bowel DiseaseSemantic proximity Read ↗

The gut microbiota and inflammatory bowel diseaseSemantic proximity Read ↗

Strategies to Dissect Host-Microbial Immune Interactions That Determine Mucosal Homeostasis vs. Intestinal Inflammation in Gnotobiotic MiceSemantic proximity Read ↗

Gut Microbiota, Low-grade Inflammation, and Metabolic SyndromeSemantic proximity Read ↗

Microorganisms linked to inflammatory bowel disease-associated dysbiosis differentially impact host physiology in gnotobiotic miceSemantic proximity Read ↗

Commensal Bacteroides species induce colitis in host-genotype-specific fashion in a mouse model of inflammatory bowel disease.Semantic proximity Read ↗

Intestinal inflammation and altered gut microbiota associated with inflammatory bowel disease renders mice susceptible to <i>Clostridioides difficile</i> colonization and infectionSemantic proximity Read ↗

Dysbiosis of the gut micro-flora aggravates symptoms and accelerates disease progression in MASLD-IBD Co-morbid mice through host-microbial metabolic imbalanceSemantic proximity Read ↗

Unravelling specific diet and gut microbial contributions to inflammatory bowel diseaseSemantic proximity Read ↗

Host-microbial Cross-talk in Inflammatory Bowel DiseaseSemantic proximity Read ↗

High-throughput clone library analysis of the mucosa-associated microbiota reveals dysbiosis and differences between inflamed and non-inflamed regions of the intestine in inflammatory bowel diseaseSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.