Article
Analysis of ICAM-1 rs3093030, VCAM-1 rs3783605, and E-Selectin rs1805193 Polymorphisms in African Women Living with HIV and Preeclampsia.
International journal of molecular sciences - 9 Oct 2024
Sibiya Samukelisiwe, Mlambo Zinhle Pretty, Mthembu Mbuso Herald, Mkhwanazi Nompumelelo P, Naicker Thajasvarie
Abstract excerpt
Intercellular adhesion molecule-1 (ICAM-1), vascular adhesion molecule-1 (VCAM-1), and E-selectin are cell adhesion molecules that play a significant role in inflammation and are implicated in the pathophysiology of preeclampsia development and HIV infection. More specifically, the immune expression of ICAM-1, VCAM-1, and E-selectin within cyto- and syncytiotrophoblast cells are dysregulated in preeclampsia,...
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