Article
Dissecting the domain structure of the regulatory subunit of cAMP-dependent protein kinase I and elucidating the role of MgATP.
The Journal of biological chemistry - 25 Mar 1990
Ringheim G E, Taylor S S
Abstract excerpt
A truncated regulatory subunit of cAMP-dependent protein kinase I was constructed which contained deletions at both the carboxyl terminus and at the amino terminus. The entire carboxyl-terminal cAMP-binding domain was deleted as well as the first 92 residues up to the hinge region. This monomeric truncated protein still forms a complex with the catalytic subunit, and activation of this complex is mediated by...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
