Mechanism of enhanced melibiose transport rate catalyzed by an Escherichia coli lactose carrier mutant with leucine substituted for serine-306. The pH-dependence of melibiose efflux.

doi:10.1016/0005-2736(90)90288-y

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Article

Mechanism of enhanced melibiose transport rate catalyzed by an Escherichia coli lactose carrier mutant with leucine substituted for serine-306. The pH-dependence of melibiose efflux.

Biochimica et biophysica acta - 1 Mar 1990

King S C, Wilson T H

Abstract excerpt

The mechanism of melibiose transport was studied in cells containing plasmid pAA22 which expresses the mutant lactose carrier (serine-306 to leucine) cloned from Escherichia coli AA22. These studies were of interest because several lines of evidence suggested that the AA22 mutation conferred nove...

Topics

Biological Transport
Cloning, Molecular
Disaccharides
Escherichia coli
Escherichia coli Proteins
Hydrogen-Ion Concentration
Kinetics
Leucine
Melibiose
Membrane Transport Proteins
Monosaccharide Transport Proteins
Mutation
Plasmids
Protons
Serine
Symporters

Source

Open in PubMed

Identifiers

PMID: 2156561
DOI: 10.1016/0005-2736(90)90288-y

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-2156561-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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