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Article

TNFRSF1A coding variants in multiple sclerosis.

Journal of neuroimmunology - 1 Jun 2011

Goris An, Fockaert Niels, Cosemans Leentje, Clysters Katleen, Nagels Guy, Boonen Steven, Thijs Vincent, Robberecht Wim, Dubois Bénédicte

Abstract excerpt

Patients with the autoinflammatory disease Tumour Necrosis Factor receptor-associated periodic syndrome (TRAPS) who suffer from demyelinating disease have been described, and one of the milder TRAPS mutations (R92Q in the TNFRSF1A gene) has been suggested as a risk factor for multiple sclerosis (MS). In a study population of 967 MS patients and 1022 controls, we replicate association [P=5×10⁻⁴, 3% in patients...

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Identifiers

PMID: 21565411
DOI: 10.1016/j.jneuroim.2011.04.005

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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