Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The filaggrin null genotypes R501X and 2282del4 seem not to be associated with psoriasis: results from general population study and meta-analysis.

Journal of the European Academy of Dermatology and Venereology : JEADV - 1 Jun 2012

Thyssen J P, Johansen J D, Carlsen B C, Linneberg A, Meldgaard M, Szecsi P B, Stender S, Menné T

Abstract excerpt

BACKGROUND: Psoriasis vulgaris could be associated with the filaggrin null genotype since certain known susceptibility loci for psoriasis are shared with susceptibility loci for atopic dermatitis. Furthermore, filaggrin expression is lowered in psoriatic skin lesions but normally expressed in uninvolved skin. So far five relatively small patient-based case-control studies have rejected a possible association...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adolescent
Share to Denmark

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Filaggrin Proteins

Share to Intermediate Filament Proteins

Share to Population Surveillance

Share to Psoriasis

Share to Surveys and Questionnaires

Share to Young Adult

Source

Identifiers

PMID: 21564328
DOI: 10.1111/j.1468-3083.2011.04107.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The filaggrin null genotypes R501X and 2282del4 seem not to be associated with psoriasis: results from general population study and meta-analysis.PMID 21564328Read ↗

Individuals who are homozygous for the 2282del4 and R501X filaggrin null mutations do not always develop dermatitis and complete long-term remission is possible.Semantic proximity Read ↗

[FILAGGRIN GENE NULL-MUTATIONS AND ATOPIC DISEASES].Semantic proximity Read ↗

Low frequency of filaggrin null mutations in Croatia and their relation with allergic diseases.Semantic proximity Read ↗

Loss-of-function variants of the filaggrin gene are not major susceptibility factors for psoriasis vulgaris or psoriatic arthritis in German patients.Semantic proximity Read ↗

[Filaggrin gene mutations are frequent and increase the risk of skin disease].Semantic proximity Read ↗

Filaggrin gene defects are independent risk factors for atopic asthma in a Polish population: a study in ECAP cohort.Semantic proximity Read ↗

Filaggrin null alleles are not associated with hand eczema or contact allergy.Semantic proximity Read ↗

The clinical relevance of filaggrin mutations: Effect on allergic disease.Semantic proximity Read ↗

Filaggrin null alleles are not associated with psoriasis.Semantic proximity Read ↗

Filaggrin null mutations and association with contact allergy and allergic contact dermatitis: results from a tertiary dermatology clinic.Semantic proximity Read ↗

Loss-of-function variants of the filaggrin gene are associated with atopic eczema and associated phenotypes in Swedish families.Semantic proximity Read ↗

Filaggrin null mutations associate with increased frequencies of allergen-specific CD4+ T-helper 2 cells in patients with atopic eczema.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.