Article
The two domains of centrin have distinct basal body functions in Tetrahymena.
Molecular biology of the cell - 1 Jul 2011
Vonderfecht Tyson, Stemm-Wolf Alexander J, Hendershott Melissa, Giddings Thomas H, Meehl Janet B, Winey Mark
Abstract excerpt
The basal body is a microtubule-organizing center responsible for organizing the cilium, a structure important for cell locomotion and sensing of the surrounding environment. A widely conserved basal body component is the Ca(2+)-binding protein centrin. Analyses of centrin function suggest a role in basal body assembly and stability; however, its molecular mechanisms remain unclear. Here we describe a mutagenic...
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