Article
The two human centrin homologues have similar but distinct functions at Tetrahymena basal bodies.
Molecular biology of the cell - 1 Dec 2012
Vonderfecht Tyson, Cookson Michael W, Giddings Thomas H, Clarissa Christina, Winey Mark
Abstract excerpt
Centrins are a ubiquitous family of small Ca(2+)-binding proteins found at basal bodies that are placed into two groups based on sequence similarity to the human centrins 2 and 3. Analyses of basal body composition in different species suggest that they contain a centrin isoform from each group. We used the ciliate protist Tetrahymena thermophila to gain a better understanding of the functions of the two centrin...
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