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Article

MicroRNA expression profiles of head and neck squamous cell carcinoma with docetaxel‐induced multidrug resistance

29 Nov 2010

Abstract excerpt

BACKGROUND: The purpose of this study was to investigate the potential role of variable microRNA (miRNA) expression in the development of multidrug resistance (MDR) in head and neck cancer. METHODS: Head and neck squamous cell carcinoma cell lines UMSCC-1 and SQ20B were treated with docetaxel at increasing concentrations to develop resistant cell lines. Parental and resistant cells were treated with cisplatin,...

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PMID: 21560177
DOI: 10.1002/hed.21540

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