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Article

RcsAB is a major repressor of Yersinia biofilm development through directly acting on hmsCDE, hmsT, and hmsHFRS.

Scientific reports - 1 Apr 2015

Fang Nan, Yang Huiying, Fang Haihong, Liu Lei, Zhang Yiquan, Wang Li, Han Yanping, Zhou Dongsheng, Yang Ruifu

Abstract excerpt

Biofilm formation in flea gut is important for flea-borne transmission of Yersinia pestis. There are enhancing factors (HmsHFRS, HmsCDE, and HmsT) and inhibiting one (HmsP) for Yersinia pestis biofilm formation. The RcsAB regulatory complex acts as a repressor of Yesinia biofilm formation, and adaptive pseudogenization of rcsA promotes Y. pestis to evolve the ability of biofilm formation in fleas. In this study,...

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Identifiers

PMID: 25828910
DOI: 10.1038/srep09566
PMCID: PMC4381331

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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