Article
Protein recognition sites in polyomavirus enhancer: formation of a novel site for NF-1 factor in an enhancer mutant and characterization of a site in the enhancer D domain.
The EMBO journal - 1 Mar 1990
Caruso M, Iacobini C, Passananti C, Felsani A, Amati P
Abstract excerpt
Polyomavirus mutants selected for modified host range exhibit DNA sequence alterations in the regulatory region, which consist mainly of duplications and/or deletions. Single base pair mutations have also been observed, which create or abolish DNA sequence motifs recognized by DNA-binding regulat...
Topics
- Animals
- Base Sequence
- Cell Line
- Cell Nucleus
- Cells, Cultured
- DNA, Viral
- Deoxyribonuclease I
- Enhancer Elements, Genetic
- Genes, Regulator
- Mice
- Molecular Sequence Data
- Mutation