Article
Molecular genetic characterization of the merozoite surface protein 1 Gene of Plasmodium vivax from reemerging Korean isolates.
Clinical and vaccine immunology : CVI - 1 May 2009
Kim So-Hee, Hwang Seung-Young, Shin Jeong Hwan, Moon Chi-Sook, Kim Dong-Wook, Kho Weon-Gyu
Abstract excerpt
Plasmodium vivax merozoite surface protein 1 (PvMSP-1) has been considered a major candidate for the development of an antimalaria vaccine, but the molecule exhibits antigenic diversity among isolates. The extent of genetic polymorphism in the region between interspecies conserved blocks 4 and 5 (ICB4 and ICB5) of the PvMSP-1 gene was analyzed for 30 Korean isolates. Two genotypes, SK-A and SK-B, were identified...
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