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Determination of multiple-clone infection at allelic dimorphism site of Plasmodium vivax merozoite surface protein-1 in the Republic of Korea by pyrosequencing assay.

Acta tropica - 1 Dec 2017

Dinzouna-Boutamba Sylvatrie-Danne, Lee Sanghyun, Son Ui-Han, Yun Hae Soo, Joo So-Young, Jeong Sookwan, Rhee Man Hee, Kwak Dongmi, Xuan Xuenan, Hong Yeonchul, Chung Dong-Il, Goo Youn-Kyoung

Abstract excerpt

Allelic diversity leading to multiple gene polymorphisms of vivax malaria parasites has been shown to greatly contribute to antigenic variation and drug resistance, increasing the potential for multiple-clone infections within the host. Therefore, to identify multiple-clone infections and the predominant haplotype of Plasmodium vivax in a South Korean population, P. vivax merozoite surface protein-1 (PvMSP-1) was...

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PMID: 28847673
DOI: 10.1016/j.actatropica.2017.08.020

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