Article
Medaka cleavage embryos are capable of generating ES-like cell cultures.
International journal of biological sciences - 15 Apr 2011
Li Zhendong, Bhat Narayani, Manali Dwarakanath, Wang Danke, Hong Ni, Yi Meisheng, Ge Ruowen, Hong Yunhan
Abstract excerpt
Mammalian embryos at the blastocyst stage have three major lineages, which in culture can give rise to embryonic stem (ES) cells from the inner cell mass or epiblast, trophoblast stem cells from the trophectoderm, and primitive endoderm stem cells. None of these stem cells is totipotent, because they show gene expression profiles characteristic of their sources and usually contribute only to the lineages of their...
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