Article
Genome-wide association scan for survival on dialysis in African-Americans with type 2 diabetes.
American journal of nephrology - 1 Jan 2011
Murea Mariana, Lu Lingyi, Ma Lijun, Hicks Pamela J, Divers Jasmin, McDonough Caitrin W, Langefeld Carl D, Bowden Donald W, Freedman Barry I
Abstract excerpt
BACKGROUND: African-Americans (AAs) with diabetes have high incidence rates of end-stage renal disease (ESRD) with associated high mortality. Genetic factors modulating the risk of mortality on dialysis are poorly understood. METHODS: A genome-wide association study was performed in 610 AAs with type 2 diabetes (T2D) and ESRD on dialysis, using the Affymetrix 6.0 platform (868,155 SNPs). Time to death was...
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