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Article

Phenotypic and functional evaluation of CD3+CD4-CD8- T cells in human CD8 immunodeficiency.

Haematologica - 1 Aug 2011

Bernardo Iván, Mancebo Esther, Aguiló Ignacio, Anel Alberto, Allende Luis M, Guerra-Vales Juan M, Ruiz-Contreras Jesús, Serrano Antonio, Talayero Paloma, de la Calle Oscar, Gonzalez-Santesteban Cecilia, Paz-Artal Estela

Abstract excerpt

BACKGROUND: Human CD8 immunodeficiency is characterized by undetectable CD8(+) lymphocytes and an increased population of CD4(-)CD8(-) (double negative) T lymphocytes. DESIGN AND METHODS: We hypothesized that the double negative subset corresponds to the cellular population that should express CD8 and is committed to the cytotoxic T lymphocyte lineage. To assess this, we determined the phenotype and function of...

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Share to CD8 Antigens
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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Share to Cytotoxicity, Immunologic

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Share to Receptors, Antigen, T-Cell

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Source

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Identifiers

PMID: 21546492
DOI: 10.3324/haematol.2011.041301
PMCID: PMC3148914

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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