Article
MTHFR, MTR, and MTHFD1 gene polymorphisms compared to homocysteine and asymmetric dimethylarginine concentrations and their metabolites in epileptic patients treated with antiepileptic drugs.
Seizure - 1 Sept 2011
Sniezawska Aleksandra, Dorszewska Jolanta, Rozycka Agata, Przedpelska-Ober Elzbieta, Lianeri Margarita, Jagodzinski Pawel P, Kozubski Wojciech
Abstract excerpt
PURPOSE: The purpose of the study was to determine the frequency of occurrence of polymorphisms of genes MTHFR (C677T), MTR (A2756G), and MTHFD1 (G1958A), as well as to analyze the concentration of homocysteine (Hcy), methionine (Met), asymmetric dimethylarginine (ADMA), and arginine (Arg) in epileptics treatment with antiepileptic drugs (AEDs), and controls. METHOD: The study included 65 epileptic patients...
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