Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A requirement of TolC and MDR efflux pumps for acid adaptation and GadAB induction in Escherichia coli.

PloS one - 26 Apr 2011

Deininger Kari N W, Horikawa Akina, Kitko Ryan D, Tatsumi Ryoko, Rosner Judah L, Wachi Masaaki, Slonczewski Joan L

Abstract excerpt

BACKGROUND: The TolC outer membrane channel is a key component of several multidrug resistance (MDR) efflux pumps driven by H(+) transport in Escherichia coli. While tolC expression is under the regulation of the EvgA-Gad acid resistance regulon, the role of TolC in growth at low pH and extreme-a...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Acids
Share to Bacterial Outer Membrane Proteins
Share to Drug Resistance, Multiple

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Enzyme Induction

Share to Escherichia coli K12

Share to Glutamate Decarboxylase

Share to Glutamates

Share to Microbial Viability

Source

Open in PubMed Open full text

Identifiers

PMID: 21541325
DOI: 10.1371/journal.pone.0018960
PMCID: PMC3082540

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-21541325-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A requirement of TolC and MDR efflux pumps for acid adaptation and GadAB induction in Escherichia coli.PMID 21541325Read ↗

Characterization of Enterohemorrhagic Escherichia coli Strains Based on Acid Resistance PhenotypesSemantic proximity Read ↗

Control of acid resistance in Escherichia coli.Semantic proximity Read ↗

Products of the Escherichia coli acid fitness island attenuate metabolite stress at extremely low pH and mediate a cell density-dependent acid resistance.Semantic proximity Read ↗

Divergent evolution of the activity and regulation of the glutamate decarboxylase systems in Listeria monocytogenes EGD-e and 10403S: roles in virulence and acid tolerance.Semantic proximity Read ↗

Coordinated regulation of acid resistance in Escherichia coli.Semantic proximity Read ↗

New insight into acid-resistant enzymes from natural mutations of Escherichia coli Nissle 1917.Semantic proximity Read ↗

The glutamate-dependent acid resistance system of Escherichia coli and Shigella flexneri is inhibited in vitro by L-trans-pyrrolidine-2,4-dicarboxylic acid.Semantic proximity Read ↗

The hdeD Gene Represses the Expression of Flagellum Biosynthesis via LrhA in Escherichia coli K-12.Semantic proximity Read ↗

Acidification of Cytoplasmic pH in <i>Escherichia coli</i> Provides a Strategy to Cope with Stress and Facilitates Development of Antibiotic ResistanceSemantic proximity Read ↗

A novel RofA-family transcriptional regulator, GadR, controls the development of acid resistance in <i>Listeria monocytogenes</i>Semantic proximity Read ↗

Presence of GadD1 glutamate decarboxylase in selected Listeria monocytogenes strains is associated with an ability to grow at low pH.Semantic proximity Read ↗

Gain-of-Function Mutations in Acid Stress Response (evgS) Protect Escherichia coli from Killing by Gallium Nitrate, an Antimicrobial Candidate.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.