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Assessing the clinical role of genetic markers of early-onset prostate cancer among high-risk men enrolled in prostate cancer early detection.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Jan 2012

Hughes Lucinda, Zhu Fang, Ross Eric, Gross Laura, Uzzo Robert G, Chen David Y T, Viterbo Rosalia, Rebbeck Timothy R, Giri Veda N

Abstract excerpt

BACKGROUND: Men with familial prostate cancer and African American men are at risk for developing prostate cancer at younger ages. Genetic markers predicting early-onset prostate cancer may provide clinically useful information to guide screening strategies for high-risk men. We evaluated clinical information from six polymorphisms associated with early-onset prostate cancer in a longitudinal cohort of high-risk...

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PMID: 22144497
DOI: 10.1158/1055-9965.EPI-11-0727
PMCID: PMC3253936

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