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Article

Genetic determinants in hepatitis C virus-associated mixed cryoglobulinemia: role of polymorphic variants of BAFF promoter and Fcγ receptors.

Arthritis and rheumatism - 1 May 2011

Gragnani Laura, Piluso Alessia, Giannini Carlo, Caini Patrizio, Fognani Elisa, Monti Monica, Petrarca Antonio, Ranieri Jessica, Razzolini Giulia, Froio Valentina, Laffi Giacomo, Zignego Anna Linda

Abstract excerpt

OBJECTIVE: Mixed cryoglobulinemia (MC) is a hepatitis C virus (HCV)-related immune complex disorder. Only some HCV-infected patients develop MC, which suggests that the genetic background of the host plays a key role. This study was undertaken to evaluate the contribution of host genetic factors in the pathogenesis of HCV-associated MC (HCV-MC) by analyzing allelic variants of low-affinity Fcγ receptor (FcγR)...

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Share to Antigen-Antibody Complex
Share to B-Cell Activating Factor

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Enzyme-Linked Immunosorbent Assay

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Share to Promoter Regions, Genetic

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Identifiers

PMID: 21538321
DOI: 10.1002/art.30274

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Genetic determinants in hepatitis C virus-associated mixed cryoglobulinemia: role of polymorphic variants of BAFF promoter and Fcγ receptors.PMID 21538321Read ↗

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