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Article

Deciphering the genetic predisposition to primary sclerosing cholangitis.

Seminars in liver disease - 1 May 2011

Karlsen Tom H, Kaser Arthur

Abstract excerpt

Genetic variants within the major histocompatibility complex (MHC) on chromosome 6 have been shown to confer risk for primary sclerosing cholangitis (PSC) ~30 years ago. However, robust genetic associations outside this genetic region have been difficult to establish. By genome-wide association analysis, a surprising large overlap of genetic risk loci outside of the MHC with prototypical autoimmune diseases has...

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Identifiers

PMID: 21538284
DOI: 10.1055/s-0031-1276647

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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