Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetics of hepatobiliary carcinogenesis.

Seminars in liver disease - 1 May 2011

Nault Jean-Charles, Zucman-Rossi Jessica

Abstract excerpt

Hepatocellular carcinoma (HCC) and cholangiocarcinoma (CC) are two leading causes of cancer death in the world. Liver carcinogenesis is driven by genetic alterations in combination with viral and environmental factors. β-catenin and P53 mutations represent the two main genetic alterations described in HCC, and P53 and KRAS mutations in CC, but rare genetic alterations could be particularly valuable if they...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bile Duct Neoplasms
Share to Bile Ducts, Intrahepatic
Share to Carcinoma, Hepatocellular

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Cholangiocarcinoma

Share to Liver Neoplasms

Share to Molecular Targeted Therapy

Share to Patient Selection

Share to Precision Medicine

Source

Identifiers

PMID: 21538283
DOI: 10.1055/s-0031-1276646

Genes

EGFR
KRAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetics of hepatobiliary carcinogenesis.PMID 21538283Read ↗

Molecular and functional genetics of hepatocellular carcinoma.Semantic proximity Read ↗

Genetics of hepatocellular carcinomaSemantic proximity Read ↗

Molecular Pathogenesis of Hepatocellular CarcinomaSemantic proximity Read ↗

An Update on the Molecular Genetics of Hepatocellular CarcinomaSemantic proximity Read ↗

The pathogenesis of hepatocellular carcinoma.Semantic proximity Read ↗

Global Epidemiology and Genetics of Hepatocellular CarcinomaSemantic proximity Read ↗

Genetics of Hepatocellular Carcinoma: From Tumor to Circulating DNASemantic proximity Read ↗

Molecular genomic landscapes of hepatobiliary cancer.Semantic proximity Read ↗

Genetic heterogeneity in cholangiocarcinoma: a major challenge for targeted therapies.Semantic proximity Read ↗

Hepatocarcinoma: genetic and epigenetic featuresSemantic proximity Read ↗

The changing landscape of hepatocellular carcinoma: etiology, genetics, and therapy.Semantic proximity Read ↗

Genetic Landscape of Multistep HepatocarcinogenesisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.