Article
Effect of the EBNA-2 gene on the surface antigen phenotype of transfected EBV-negative B-lymphoma lines.
International journal of cancer - 15 Jan 1990
Aman P, Rowe M, Kai C, Finke J, Rymo L, Klein E, Klein G
Abstract excerpt
Two EBV-negative B-lymphoma cell lines with different phenotypes were transfected with the Epstein-Barr virus EBNA-2 gene. The effects on the expression of 8 B-cell surface markers were analyzed by immunofluorescence methods. In one of the EBNA-2 transfected cell lines, the expression of the CR2...
Topics
- Antibodies, Monoclonal
- Antibodies, Viral
- Antigens, Neoplasm
- Antigens, Surface
- B-Lymphocytes
- Cell Line
- Cosmids
- Electrophoresis, Polyacrylamide Gel
- Fluorescent Antibody Technique
- Gene Expression Regulation, Viral
- Genes, Viral
- Genetic Vectors
- Herpesvirus 4, Human
- Humans
- Immunoblotting
- Lymphoma
- Phenotype
- Transfection