Article
Molecular characterization of drug-resistant Mycobacterium tuberculosis isolates circulating in China by multilocus PCR and electrospray ionization mass spectrometry.
Journal of clinical microbiology - 1 Jul 2011
Wang Feifei, Massire Christian, Li Haijing, Cummins Lendell L, Li Feng, Jin Jialin, Fan Xiaoping, Wang Sen, Shao Lingyun, Zhang Shu, Meng Shufang, Wu Jing, Lu Chanyi, Blyn Lawrence B, Sampath Rangarajan, Ecker David J, Zhang Wenhong, Tang Yi-Wei
Abstract excerpt
We used multilocus PCR and electrospray ionization mass spectrometry (PCR/ESI-MS) to determine the genotype and drug resistance profiles for 96 Mycobacterium tuberculosis isolates circulating in regions of high and low tuberculosis (TB) endemicity in China. The dominant principal genetic group (PGG) circulating in China was PGG1, and drug-resistant gene mutations were more diversified in the region of low rather...
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