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Celiac disease and HLA typing using real‐time PCR with melting curve analysis

27 Apr 2011

Abstract excerpt

Celiac disease (CD) is an autoimmune disease characterized by chronic diarrhea, inflammatory lesions of small bowel and nutritional malabsorption. CD is strongly associated with the presence of HLA-DQB*02, DQB*03:02 and DQA*05. The absence of any one of these three human leukocyte antigen (HLA) alleles rules out the diagnosis of CD in suspected patients. Here, we describe a novel method to detect the presence of...

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PMID: 21521178
DOI: 10.1111/j.1399-0039.2011.01676.x

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