Missense mutations at lysine 350 in beta 2-tubulin confer altered sensitivity to microtubule inhibitors in Chlamydomonas.

doi:10.1105/tpc.2.11.1051

Back to search

Article

Missense mutations at lysine 350 in beta 2-tubulin confer altered sensitivity to microtubule inhibitors in Chlamydomonas.

The Plant cell - 1 Nov 1990

Lee V D, Huang B

Abstract excerpt

Two beta-tubulin mutants of Chlamydomonas reinhardtii, colR4 and colR15, were previously isolated in our laboratory. Each mutant expressed an acidic beta-tubulin variant as a result of an alteration in the coding sequence of one of the two beta-tubulin genes in C. reinhardtii, which in the wild t...

Topics

Amino Acid Sequence
Animals
Base Sequence
Chlamydomonas reinhardtii
Cloning, Molecular
Colchicine
Drug Resistance
Gene Library
Lysine
Molecular Sequence Data
Mutation
Tubulin

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.