Article
APEX microarray panel for genotyping polymorphisms in cancer chemotherapy and estimation frequencies in a Slovak population.
Pharmacogenomics - 1 Apr 2011
Soltysova Andrea, Minarik Gabriel, Dzurenkova Alica, Sufliarska Sabina, Kadasi Ludevit, Turna Jan, Mladosievicova Beata
Abstract excerpt
AIM: Many studies focus on monitoring response to chemotherapy, adverse effects and prediction of therapeutic effects, which depend on individual gene variability. The amount of various polymorphisms in genes involved in the folate cycle, and other metabolic pathways involved in the metabolism of chemotherapeutic drugs, are an essential topic of such studies. This work focuses on the design and establishment of a...
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