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Article

A synthetic homing endonuclease-based gene drive system in the human malaria mosquito.

Nature - 12 May 2011

Windbichler Nikolai, Menichelli Miriam, Papathanos Philippos Aris, Thyme Summer B, Li Hui, Ulge Umut Y, Hovde Blake T, Baker David, Monnat Raymond J, Burt Austin, Crisanti Andrea

Abstract excerpt

Genetic methods of manipulating or eradicating disease vector populations have long been discussed as an attractive alternative to existing control measures because of their potential advantages in terms of effectiveness and species specificity. The development of genetically engineered malaria-resistant mosquitoes has shown, as a proof of principle, the possibility of targeting the mosquito's ability to serve as...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 21508956
DOI: 10.1038/nature09937
PMCID: PMC3093433

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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