Article
Association of the PTPN22 gene polymorphism with autoantibody positivity in Turkish rheumatoid arthritis patients.
Tissue antigens - 1 Jul 2011
Ates A, Karaaslan Y, Karatayli E, Ertuğrul E, Aksaray S, Türkyilmaz A, Ozet G
Abstract excerpt
The PTPN22 C1858T gene polymorphism has been recently reported to be associated with rheumatoid arthritis (RA) in European and North American ancestry. In contrast, the frequency of PTPN22 C1858T polymorphism is extremely rare in Asian and African populations. As the genetic heterogeneity between populations is clearly present in RA, we wanted to investigate whether the PTPN22 C1858T polymorphism is associated...
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