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Article

Mutational and clinico-pathological analysis of papillary thyroid carcinoma in Serbia.

Endocrine journal - 1 Jan 2011

Stanojevic Boban, Dzodic Radan, Saenko Vladimir, Milovanovic Zorka, Pupic Gordana, Zivkovic Ognjen, Markovic Ivan, Djurisic Igor, Buta Marko, Dimitrijevic Bogomir, Rogounovitch Tatiana, Mitsutake Norisato, Mine Mariko, Shibata Yoshisada, Nakashima Masahiro, Yamashita Shunichi

Abstract excerpt

Molecular pathogenesis of papillary thyroid carcinoma (PTC) is largely associated with mutational changes in the BRAF, RAS family and RET genes. Our aim was to assess clinico-pathological and prognostic correlations of these PTC-specific gene alterations, with a particular emphasis on the BRAF mutation, in a group of 266 Serbian PTC patients, for the first time. The reference center-based retrospective cohort...

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Identifiers

PMID: 21498916
DOI: 10.1507/endocrj.k11e-054

Genes

BRAF
RET

Variants

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