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Article

Genetic amplification of the vascular endothelial growth factor (VEGF) pathway genes, including <i>VEGFA</i>, in human osteosarcoma

14 Apr 2011

Abstract excerpt

BACKGROUND: Osteosarcoma is the most common primary tumor of bone. It is a highly vascular and extremely destructive malignancy that mainly affects children and young adults. The authors conducted microarray-based comparative genomic hybridization (aCGH) and pathway analyses to gain a systemic view of pathway alterations in the genetically altered genes. METHODS: Recurrent amplified and deleted genes that were...

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PMID: 21495021
DOI: 10.1002/cncr.26116

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